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NataPro is ChiHonBio's Mark. Natamycin is a fungicidal antimycotic of the polyene macrolide group. It is produced by the species of Streptomyces and multistep extracted.

Application areas

NataPro is effective in a variety of food products across a wide range of pH levels(3.5-9.5).Natamycin is currently approved by the FDA for use on the surface of cuts and slices of cheese where the standards for such cheese provides for the use of safe and suitable mold inhibiting ingredients. According FDA,72.155, 1994. spraying 200-300mg/kg water solution on the surface of the cheese slice. According GB2760-1997: spraying (or digging in) 200~300mg/kg mixed fluid suspension to the surface of cheese, meat food, meat soup, ham, flavor moon cakes, fresh juice, easily-moulded food, and

various food processing devices. Residual less than 10mg/kg.

Potential benefits

Natamycin are effective anti-microbial agents. Using Natamycin as food preservatives can:
● Enhance the quality of food product, and significantly extend the shelf life of foods by preventing yeast and mould
● Reduce product being recalled resulting from spoilage (and reduces manufacturing costs)
● Replace or partial replace chemical preservatives and meet consumer demand for food preserved with natural
● Have no adverse flavour to foods
● Have stronger inhibitability compared to sorbic acid
● Prevent formation of potentially carcinogenic mycotoxins
● Cover a very broad spectrum of activity -- most yeasts and moulds are sensitive to very low levels of the preservative
(<1 - 20 ppm)
● Do not act against bacteria .This makes it useful for food products such as cheese and dry sausages in which bacteria
are key to the ripening process
● Remain on food surface for a long time where contamination usually occurs
● Be proven to be a safe antimycotic agent.

Registered Index:CAS[7681-93-8];INS 235;EEC No. 235

Natamycin Molecular formula: C33H47NO13

Natamycin Molecular weight: 665.74


1. ADI 0~0.3mg/kg (FAO/WHO, 1994)
2. Safe to apply on food (FDA, §172.155, 1994)

3. LD50 2.73g/kg (experiment with matured male mouse)

NataPro is composed of:

Natamycin min. 89%
Water max. 8%

All percentages are by weight.

Quity Stand:

Items Standard
Appearance White to off white Powder No. taste
Assay(On anhydrous base) ≥95%
PH 5.0—7.5
Water ≤8%
Total Plate Count . ≤100CFU/G Max
E. Coli Negative In 25g
Salmonella Negative In 25g
Listeria monocyt Negative In 25g
Ash 0.5%
Particle size 90% 5μm
Heavy metals ≤10PPM
Arsenic (As) ≤3PPM
Mercury (Hg) ≤1PPM
Lead (Pb) ≤2PPM


1000g*Aluminium barrel/carton; as customers request.


Store unopened under 20℃ In dry conditions, away from direct sunlight. When opened, store under 20℃ in original container in dry conditions, away from direct sunlight. Shelf life is 18 months when stored according to recommendations.